3D bioprinting yog lub chaw tsim khoom siab heev uas tuaj yeem siv los luam cov ntaub so ntswg los ntawm cov hlwb thiab qhov kawg ntawm lub cev.Qhov no tuaj yeem qhib lub ntiaj teb tshiab hauv cov tshuaj thaum muaj txiaj ntsig ncaj qha rau cov neeg mob uas xav tau kev hloov khoom nruab nrog cev.
Tsis txhob tos tus neeg pub dawb los yog pheej hmoo rau lub cev tsis lees txais cov khoom hloov pauv, cov neeg mob muaj lub hom phiaj tsim lub cev los hloov lub cev tsis zoo.Txawm li cas los xij, txawm tias nrog kev nce qib hauv 3D bioprinting dhau 20 xyoo dhau los, nws tseem tsis muaj kev vam meej tseem ceeb txhawm rau tsim cov ntaub so ntswg 3D biomimetic complex.
Raws li cov kws tshawb fawb ntawm Singapore University of Technology thiab Design (SUTD), Nanyang Technological University (NTU) thiab Asia University, cov ntaub so ntswg kab lis kev cai thev naus laus zis tshwj xeeb yuav tsum tau ua kom nrawm los hais txog lub caj dab hauv kev loj hlob bioprinted multicellular 3D cov ntaub so ntswg tsim rau hauv cov ntaub so ntswg ua haujlwm.Lawv cov ntawv tshawb fawb, hu ua "Print me an organ!Vim li cas peb tseem tsis tau tshwm sim?tau luam tawm hauv Advances in Polymer Science.
Hauv daim ntawv no, cov kws tshawb fawb kuj tseem muab kev tshuaj xyuas qhov tob ntawm kev txhim kho tsis ntev los no thiab tshuaj xyuas cov thev naus laus zis bioprinting.Qhov kev nce qib hauv bioink kev loj hlob, kev siv cov tswv yim tshiab bioprinting thiab cov tswv yim kev loj hlob ntawm cov ntaub so ntswg kuj raug tshuaj xyuas.Kev saib xyuas tshwj xeeb kuj tau muab rau lub luag haujlwm ntawm kev tshawb fawb polymer thiab yuav ua li cas ntxiv 3D bioprinting kom kov yeej qee qhov teeb meem loj hauv kev luam ntawv hauv nruab nrog cev, xws li ua kom muaj biomimetic, angiogenesis thiab 3D anatomy-txog kev lom neeg cov qauv (raws li cov duab hauv qab no qhia. ).
Kev siv cov tswv yim ntxiv, xws li kev sib koom ua ke ntawm kev coj noj coj ua, yog suav tias yog qhov tseem ceeb los xyuas kom meej qhov kev loj hlob thiab sib sau ua ke ntawm cov ntaub so ntswg bioprinted.Txawm hais tias tam sim no nws muaj peev xwm tsim tau tib neeg cov ntaub so ntswg lossis cov kabmob uas tuaj yeem loj hlob mus rau hauv cov hlab ntsha thiab cov ntaub so ntswg ua haujlwm, kev lag luam tseem poob qab hauv bioprinting ntawm tib neeg cov ntaub so ntswg lossis cov kabmob vim qhov nyuaj ntawm cov ntaub so ntswg tshwj xeeb extracellular matrix ( ECM) thiab cov txheej txheem kev loj hlob ntawm cov ntaub so ntswg - tsis muaj cov kab lis kev cai tsim nyog los txhawb ntau hom cell thiab xav tau cov ntaub so ntswg ntxiv ua ntej engraftment.
"Txawm hais tias 3D bioprinting tseem nyob rau theem pib, qhov zoo tshaj plaws leaps nws tau ua nyob rau hauv xyoo tas los no qhia txog qhov kawg ntawm kev ua haujlwm hauv lub cev.Txawm li cas los xij, txhawm rau txhawm rau txhawm rau thaj tsam ntawm cov tshuaj, peb yuav tsum kov yeej cov kev cov nyom ntawm kev tsim cov ntaub so ntswg.Tshwj xeeb bioinks tsis Optimizing cov ntaub so ntswg maturation txheej txheem.Qhov no thaum kawg yuav muaj kev cuam tshuam loj heev rau lub neej ntawm cov neeg mob, ntau tus neeg yuav nyob ntawm lub neej yav tom ntej ntawm 3D bioprinting, "said Professor Chua Chee Kai, tus thawj coj ntawm daim ntawv.
JS Additive's 3D luam ntawv kev pab cuam kuj tau txuas ntxiv txhim kho thiab nce qib, uas mus txog qib siab dua hauv kev lag luam kho mob kom tau raws li cov kev xav tau ntawm cov neeg mob loj thiab kev tshawb fawb tshawb fawb.Peb cov qauv 3D luam tawm kho mob thiab cov khoom tiav kuj tau siv dav hauv cov ntawv thov txawv teb chaws.Txais tos thiab siv.